Friday, May 3, 2013

US Cellular embraces iPhone after rejecting it

(AP) ? U.S. Cellular, the only major U.S. wireless carrier to resist the iPhone, says it's going to start selling it this year.

CEO Mary Dillon announced the reversal Friday on a call with investors and analysts. She didn't specify exactly when the company would start selling Apple's phone, or what models it would carry.

A year and a half ago, Dillon said U.S. Cellular Corp. had the opportunity to carry the phone but rejected it because it was too expensive. The iPhone is more expensive than most smartphones, and phone companies absorb this cost to sell it for $199 or less.

Dillon says many of the customers leaving the Chicago-based company are doing so because it doesn't carry the iPhone. In the 18 months since she talked about rejecting the iPhone, the company has lost 268,000, or 5 percent, of its customers on contract-based plans, which are the most lucrative.

Apart from the wholesale cost of the individual phone, carriers face another obstacle: Apple requires them to commit to purchasing a minimum amount. In the case of U.S. Cellular, it has promised to buy $1.2 billion worth of iPhones over three years, according to a regulatory filing. That's roughly 2 million phones.

Investors appeared to be concerned about the cost of the phone, too. U.S. Cellular shares fell $1.08, or 2.8 percent, to $37.39 in afternoon trading. The company has its own stock listing, but is controlled by Telephone & Data Systems Inc., a phone company.

With U.S. Cellular's embrace of the iPhone, the six biggest cellphone companies in the U.S. will all be selling it. Many smaller ones do as well. The iPhone was sold exclusively by AT&T for three and a half years, and the subsequent broadening of the carrier base has been crucial in boosting Apple's sales. No. 4 T-Mobile USA was locked out of the iPhone club for a long time, but started selling it last month after a network revamp enabled the company to offer high-speed data service on the phone. U.S. Cellular is the fifth largest cellphone company, after No. 5 MetroPCS combined with T-Mobile this week.

U.S. Cellular also has a new high-speed data network, and Dillon said that was a factor in the decision to accept the iPhone.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-05-03-US%20Cellular-iPhone/id-d547929f9bd1422f8c988448b6c98b5f

andy cohen andy cohen mozambique oosthuizen great expectations jake owen oosthuizen louis

Saudi Arabia reports 7 cases of SARS-like virus

RIYADH, Saudi Arabia (AP) ? Saudi Arabia's Health Ministry said Thursday that five people have died and two other patients were in critical condition with confirmed cases of a new respiratory virus related to SARS.

The ministry said in a statement that it had informed the World Health Organization of the seven new cases of novel coronavirus.

The germ is from a family of viruses that cause the common cold, as well as SARS ? the severe acute respiratory syndrome that killed some 800 people, mostly in Asia, in a 2003 epidemic. Health experts still aren't sure how humans are being infected. The new coronavirus, which can cause acute pneumonia and kidney failure, is most closely related to a bat virus and scientists are considering whether bats or other animals like goats or camels are a possible source of infection.

Since September 2012, WHO has been informed of 24 confirmed cases. Sixteen of the patients died.

The new virus was first identified last year in the Middle East and several of the people infected had all traveled to Qatar, Saudi Arabia, Jordan or Pakistan.

WHO says the virus is probably more widespread than just the Middle East and has advised countries to test any people with unexplained pneumonia. In Saudi Arabia last year, four members of the same family fell ill and two died.

The Saudi government is conducting an ongoing investigation into the outbreak.

The seven people who contracted the virus are not from the same family and there is no indication that any of them were in contact with animals or had traveled recently.

Source: http://news.yahoo.com/saudi-arabia-reports-7-cases-sars-virus-205102800.html

martin luther king jr quotes Inauguration 2013 Tony Gonzalez Richard Blanco Anna Burns Welker Martin Luther King, Jr. Mlk Quotes

'Oil for the joints' offers hope for osteoarthritis sufferers

'Oil for the joints' offers hope for osteoarthritis sufferers [ Back to EurekAlert! ] Public release date: 2-May-2013
[ | E-mail | Share Share ]

Contact: Michael Seele
mseele@bu.edu
617-353-9766
Boston University College of Engineering

A team of researchers led by a Boston University Biomedical Engineer has developed a new joint lubricant that could bring longer lasting relief to millions of osteoarthritis sufferers. The new synthetic polymer supplements synovial fluid, the natural lubricant in joints, and works better than comparable treatments currently available.

According to Boston University Professor of Biomedical Engineering Mark W. Grinstaff, the best fluid supplement now available offers temporary symptom relief but provides inadequate lubrication to prevent further degradation of the cartilage surfaces that cushion the joint. To achieve both objectives, Grinstaff, Beth Israel Deaconess Medical Center/Harvard Medical School orthopedic surgeon Brian Snyder and a team of Boston University chemistry and engineering students, fellows and clinicians have advanced the first synthetic synovial fluid. They describe the unique polymer and its performance in Journal of the American Chemical Society.

The most common form of joint disease and a leading cause of disability in the elderly, osteoarthritis (OA) affects about 27 million Americans and 200 million people worldwide. Characterized by pain and swelling, the disease emerges in hand, hip, knee and other commonly used joints where degradation of cartilage and synovial fluid results in bone-on-bone abrasion. Treatments range from anti-inflammatory drugs to total joint replacement. While there's no cure for OA, one treatmentinjection of a polymer to supplement synovial fluid in the jointpromises to relieve symptoms and slow the disease's progression by reducing wear on cartilage surfaces.

"From our studies, we know our biopolymer is a superior lubricant in the joint, much better than the leading synovial fluid supplement, and similar to healthy synovial fluid," said Grinstaff. "When we used this new polymer, the friction between the two cartilage surfaces was lower, resulting in less wear and surface-to-surface interaction. It's like oil for the joints."

Originally produced last year for another study, the new polymer mimics some of the properties of natural polysaccharides, large compounds that link repetitive sequences of sugar molecules in a chainlike pattern.

"You put it between your fingers, and it's slippery," Grinstaff observed. "Once we made it, we wondered if we could use it as a lubricant and where it would be useful. That's how we thought of using it as a potential treatment for OA."

Another advantage of the biopolymer is its large molecular weight or size, which prevents it from seeping out of the joint, enabling longer lasting cartilage protection. Unlike the leading synovial fluid supplement, which lasts one or two days, the new polymer remains in the joint for more than two weeks.

###

The research is supported by the Wallace H. Coulter Foundation and Flex Biomedical, a startup cofounded by Grinstaff and Snyder.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


'Oil for the joints' offers hope for osteoarthritis sufferers [ Back to EurekAlert! ] Public release date: 2-May-2013
[ | E-mail | Share Share ]

Contact: Michael Seele
mseele@bu.edu
617-353-9766
Boston University College of Engineering

A team of researchers led by a Boston University Biomedical Engineer has developed a new joint lubricant that could bring longer lasting relief to millions of osteoarthritis sufferers. The new synthetic polymer supplements synovial fluid, the natural lubricant in joints, and works better than comparable treatments currently available.

According to Boston University Professor of Biomedical Engineering Mark W. Grinstaff, the best fluid supplement now available offers temporary symptom relief but provides inadequate lubrication to prevent further degradation of the cartilage surfaces that cushion the joint. To achieve both objectives, Grinstaff, Beth Israel Deaconess Medical Center/Harvard Medical School orthopedic surgeon Brian Snyder and a team of Boston University chemistry and engineering students, fellows and clinicians have advanced the first synthetic synovial fluid. They describe the unique polymer and its performance in Journal of the American Chemical Society.

The most common form of joint disease and a leading cause of disability in the elderly, osteoarthritis (OA) affects about 27 million Americans and 200 million people worldwide. Characterized by pain and swelling, the disease emerges in hand, hip, knee and other commonly used joints where degradation of cartilage and synovial fluid results in bone-on-bone abrasion. Treatments range from anti-inflammatory drugs to total joint replacement. While there's no cure for OA, one treatmentinjection of a polymer to supplement synovial fluid in the jointpromises to relieve symptoms and slow the disease's progression by reducing wear on cartilage surfaces.

"From our studies, we know our biopolymer is a superior lubricant in the joint, much better than the leading synovial fluid supplement, and similar to healthy synovial fluid," said Grinstaff. "When we used this new polymer, the friction between the two cartilage surfaces was lower, resulting in less wear and surface-to-surface interaction. It's like oil for the joints."

Originally produced last year for another study, the new polymer mimics some of the properties of natural polysaccharides, large compounds that link repetitive sequences of sugar molecules in a chainlike pattern.

"You put it between your fingers, and it's slippery," Grinstaff observed. "Once we made it, we wondered if we could use it as a lubricant and where it would be useful. That's how we thought of using it as a potential treatment for OA."

Another advantage of the biopolymer is its large molecular weight or size, which prevents it from seeping out of the joint, enabling longer lasting cartilage protection. Unlike the leading synovial fluid supplement, which lasts one or two days, the new polymer remains in the joint for more than two weeks.

###

The research is supported by the Wallace H. Coulter Foundation and Flex Biomedical, a startup cofounded by Grinstaff and Snyder.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/buco-ft050213.php

Am I registered to vote Voter registration Election Election results 2012 exit polls Presidential Polls California Propositions

Thursday, May 2, 2013

Samsung announces NX2000 Smart camera: 20.3MP, NFC, WiFi, 3.7-inch touchscreen, $650 with a 20-50mm

DNP Samsung announces NX2000

If you've been torn between Samsung's NX300 and NX1000 mirrorless cameras, you should know the company has officially split the difference with its new NX2000. While it likely won't sway NEX-3N lovers away from Sony, the $650 NX2000 is a Benjamin more than Sammy's lower-end NX1000 and packs the same 3D-capable DRIMe IV processor and NFC functionality as the pricier NX300 -- not to mention the 20.3-megapixel APC-S sensor seen across the line. The differentiating factor from its siblings is the Galaxy camera-like 3.7-inch, 1,152k-dot touchscreen (fixed) on back, rather than the usual assortment of rear buttons. Similar to the 300, the ISO range is 100 to 25,600, maximum JPG burst rate is 8fps and video tops out at 1080p HD (30fps instead of 60, however). Unfortunately, the autofocus is only contrast-detection, but Samsung is steadfast to claim that it's one of the fastest to the draw against the competition.

As you'd expect, this shooter features WiFi (single band) for the likes of interfacing with AllShare Play and a Galaxy tablet or smartphone and a MicroSD card slot for easier transferability. Sure, it's not the most exciting update to Samsung's camera line, but it's clearly a big leap up from the NX1000 -- on paper, anyway. The NX2000 will be available soon in your choice of white, black or pink and comes bundled with Adobe Lightroom 4, a 20-50mm lens and a hotshoe-powered flash. Grab more looks at the gallery below and hit the press release after the break for all the technical details.

Filed under:

Comments

Source: http://www.engadget.com/2013/05/01/samsung-nx2000/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

jerome simpson hand sanitizer obama on jimmy fallon google drive pilar sanders andrew young real life barbie

Local setbacks vex GOP governors eyeing 2016 race

WASHINGTON (AP) ? Republican governors are often seen as innovative policymakers and potential presidential candidates, but a few are struggling with political or ethical problems that might crimp their ambitions.

Two governors eyeing possible White House bids ? Bob McDonnell of Virginia and Bobby Jindal of Louisiana ? suddenly find themselves fending off critics and trying to shore up legacies they hope will withstand national scrutiny. Other high-profile governors run the gamut from maintaining solid popularity to being in danger of losing re-election next year.

Governorships can be springboards to the White House, as Ronald Reagan, Bill Clinton, George W. Bush and others have shown. But the high visibility also can lead to painful falls.

McDonnell, who built an image as a competent problem-solver, confronted questions Tuesday about an FBI inquiry into gifts he accepted from a wealthy Virginia businessman. And Jindal, even in a Republican-dominated state, had to pull back his ambitious plan to replace Louisiana's corporate and personal income taxes with higher sales taxes. His popularity has sagged lately.

The 2016 presidential election is far away, of course, and the GOP has plenty of possible contenders. They include current and former governors, such as Chris Christie of New Jersey and Jeb Bush of Florida.

Still, McDonnell's and Jindal's struggles ? combined with those of Republican governors in Pennsylvania, Florida, South Carolina and elsewhere ? prove that governorships can be far from ideal incubators of political ideas and national ambitions.

"It's a double-edge sword, being chief executive," said John Ullyot, a Republican strategist and former Senate aide from Virginia. Effective governors, he said, can implement agendas and build reputations for bipartisanship, as Christie has sometimes done in New Jersey.

"But if something goes wrong in your state," Ullyot said, "there's no one to blame but you."

Starting with McDonnell and Christie in 2009, and followed by an impressive class the following year, Republicans won gubernatorial races in numerous states carried by President Barack Obama in 2008 and 2012. They included Ohio, Pennsylvania, Michigan, Wisconsin, Florida and New Mexico.

Politically, the timing was ideal. GOP control of these battleground states enabled Republicans to dominate the once-a-decade redrawing of congressional districts after the 2010 census. It's one reason Republicans hold a 31-seat House majority even though Americans cast a million more votes last November for Democratic House candidates than for Republicans.

Some of these new GOP governors ? mostly notably John Kasich of Ohio and Scott Walker of Wisconsin ? pushed conservative agendas so fast and fiercely that the public backlash forced them to regroup and proceed more diplomatically.

Republican Govs. Tom Corbett of Pennsylvania and Rick Scott of Florida, who have lower national profiles, are among those still struggling to rebound from early problems.

McDonnell's and Jindal's woes draw notice beyond their states because they are among the half-dozen or so most-discussed Republicans in early political chatter about 2016. Democrats have ambitious governors, too, including Maryland's Martin O'Malley and New York's Andrew Cuomo. But Hillary Rodham Clinton and Vice President Joe Biden tend to dominate early Democratic talk about Obama's possible successor.

In Virginia, McDonnell had enjoyed comfortable approval ratings and was seen as a conservative pragmatist unafraid to compromise. Last winter, he achieved a landmark overhaul of the state's failing system for funding road construction and addressing acute gridlock in the Washington suburbs and the Norfolk region.

That image was rocked by Monday's news that the FBI is examining ties McDonnell and his wife, Maureen, have with a Virginia-based food supplements maker that's the subject of a federal securities probe and two shareholder lawsuits.

McDonnell told WTOP radio that his administration never gave special treatment to Star Scientific Inc. or its CEO, Jonnie Williams, who had given McDonnell more than $100,000 in political contributions and spent thousands of dollars more on personal gifts to McDonnell and his family.

Virginia law did not require the governor to disclose the $15,000 that Williams gave McDonnell's daughter Cailin for her wedding. But in his radio appearance Tuesday, McDonnell acknowledged the political sensitivity of the matter.

"I think, obviously, from the attention it has gotten, it has certainly now been disclosed," he said. He said it was hard to say whether he would ask his daughter to reject the gift if given a chance to do it over. "It's caused a fair amount of pain for me personally," McDonnell said. "I'm a governor, but I'm also a dad and I love my daughter very much."

In Louisiana, polls and anecdotal evidence suggest many people have grown tired of Jindal's national travels, state government layoffs and budget cuts, especially to health care and higher education. His sweeping tax plan drew wide criticism.

It marked a setback for the fast-talking Yale Law School graduate and Rhodes scholar, who has urged the GOP to stop being "the stupid party" that's out of step on key social matters.

In the past 50 years, more governors and vice presidents have been elected president than have sitting senators, although a few senators almost always try. Republican senators weighing possible presidential bids in 2016 include Rand Paul of Kentucky and Marco Rubio of Florida.

Republican Mitt Romney and Democrat Michael Dukakis are among the incumbent or former governors who won their party's nomination but failed to win the White House. Four of the last six presidents, however, were governors.

Republican Governors Association spokesman Jon Thompson defended his team. GOP governors, he said, are balancing budgets "while tackling energy, pension and education reform. Their successful brand of results-oriented conservatism shows why today's leaders of the GOP come from the states."

___

Lewis reported from Richmond, Va.

Source: http://news.yahoo.com/local-setbacks-vex-gop-governors-eyeing-2016-race-064504286.html

sports illustrated swimsuit 2012 aretha franklin whitney houston paul williams paul babeu kevin costner budweiser shootout animal house

Genetic mutation linked with typical form of migraine headache

May 1, 2013 ? A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.

In a paper published on May 1 in Science Translational Medicine, the team linked the mutation with evidence of migraine in humans, in a mouse model of migraine and in cell culture in the laboratory.

The mutation is in the gene known as casein kinase I delta (CKIdelta).

?This is the first gene in which mutations have been shown to cause a very typical form of migraine,? said senior investigator Louis J. Pt??ek, an investigator at HHMI and a professor of neurology at UCSF. ?It?s our initial glimpse into a black box that we don?t yet understand.?

Migraine, the causes of which are still unknown, affects 10 to 20 percent of all people, and causes ?huge losses in productivity, not to mention immense suffering,? said Pt??ek. Typical symptoms include a pounding headache; lowered pain threshold; hypersensitivity to mild stimuli including sound and touch; and aura, which Pt??ek describes as ?a visual sensation that presages the headache to come.?

The paper presents both clinical and basic scientific evidence that the mutation causes migraine.

In the study, the scientists first analyzed the genetics of two families in which migraine was common, and found that a significant proportion of migraine sufferers in the families either had the mutation or were the offspring of a mutation carrier.

In the laboratory, the team demonstrated that the mutation affects the production of the casein kinase I delta enzyme, which carries out a number of vital functions in the brain and body. ?This tells us that the mutation has real biochemical consequences,? said Pt??ek.

The scientists then investigated the effects of the mutation in a line of mice that carry it. ?Obviously, we can?t measure headache in a mouse,? Pt??ek noted, ?but there are other things that go along with migraine that we can measure.?

Pain threshold, explained Pt??ek, can be lowered in mice by the administration of nitroglycerin. The mutant mice had a significantly lower threshold for nitroglycerin-induced peripheral pain than did normal mice.

Another piece of evidence was cortical spreading depression (CSD), a wave of electrical ?silence? in the brain that follows electrical stimulation, spreading out from the point of stimulation in a predictable pattern. The researchers found that the mutant mice had a significantly lower electrical threshold for the induction of CSD.

The CSD experiments are ?especially intriguing,? said Pt??ek, because it is known that CSD spreads through the brain at 3 millimeters per minute. ?Functional brain imaging has shown that in the occipital lobes of people with migraine aura, changes in blood flow spread at the same rate.?

Finally, Pt??ek and his team found that astrocytes ? brain cells that are essential to neuronal functioning and health ? from the brains of mutant mice showed increased calcium signaling compared with astrocytes from the brains of normal mice.

?This is significant because we think astrocyte functioning is very, very relevant to migraine,? said Pt??ek. ?This is an enzyme, and so it modifies proteins. The question is, which protein or proteins does it modify that is relevant to migraine? How does it change astrocyte activity??

The research ?puts us one step closer to understanding the molecular pathway to pain in migraine,? he said. ?And, as we come to a clearer understanding, we can start thinking about better therapies. Certain molecules might be targets for new drugs.? There are good drugs now, said Pt??ek, ?but they only help some patients, some of the time. The need for better treatments is huge.?

The CKIdelta mutation is ?far from the only mutation likely to be associated with migraine,? Pt??ek cautioned. ?There are likely several, in different combinations in different people. This is simply the first one we?ve found.?

Co-authors of the paper are K.C. Brennan, MD, of UCLA and the University of Utah; Emily A. Bates, PhD, of UCSF and Brigham Young University, Utah; Robert E. Shapiro, MD, PhD, of the University of Vermont; Jekaterina Zyuzin of UCLA; William C. Hallows, PhD, Yong Huang, PhD and Hsien-Yang Lee, PhD, of UCSF; Christopher R. Jones, MD, PhD, of UU; Ying-Hui Fu, PhD, of UCSF; and Andrew Charles, MD, of UCLA.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by University of California - San Francisco, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. K. C. Brennan, E. A. Bates, R. E. Shapiro, J. Zyuzin, W. C. Hallows, Y. Huang, H.-Y. Lee, C. R. Jones, Y.-H. Fu, A. C. Charles, L. J. Ptacek. Casein Kinase I? Mutations in Familial Migraine and Advanced Sleep Phase. Science Translational Medicine, 2013; 5 (183): 183ra56 DOI: 10.1126/scitranslmed.3005784

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/YfPPxOnG9yM/130501145105.htm

michael bay zsa zsa gabor illinois primary trayvon martin 911 call kiribati vernal equinox mr rogers

Printable functional 'bionic' ear melds electronics and biology

May 1, 2013 ? Scientists at Princeton University used off-the-shelf printing tools to create a functional ear that can "hear" radio frequencies far beyond the range of normal human capability.

The researchers' primary purpose was to explore an efficient and versatile means to merge electronics with tissue. The scientists used 3D printing of cells and nanoparticles followed by cell culture to combine a small coil antenna with cartilage, creating what they term a bionic ear.

"In general, there are mechanical and thermal challenges with interfacing electronic materials with biological materials," said Michael McAlpine, an assistant professor of mechanical and aerospace engineering at Princeton and the lead researcher. "Previously, researchers have suggested some strategies to tailor the electronics so that this merger is less awkward. That typically happens between a 2D sheet of electronics and a surface of the tissue. However, our work suggests a new approach -- to build and grow the biology up with the electronics synergistically and in a 3D interwoven format."

McAlpine's team has made several advances in recent years involving the use of small-scale medical sensors and antenna. Last year, a research effort led by McAlpine and Naveen Verma, an assistant professor of electrical engineering, and Fio Omenetto of Tufts University, resulted in the development of a "tattoo" made up of a biological sensor and antenna that can be affixed to the surface of a tooth.

This project, however, is the team's first effort to create a fully functional organ: one that not only replicates a human ability, but extends it using embedded electronics.

"The design and implementation of bionic organs and devices that enhance human capabilities, known as cybernetics, has been an area of increasing scientific interest," the researchers wrote in the article which appears in the scholarly journal Nano Letters. "This field has the potential to generate customized replacement parts for the human body, or even create organs containing capabilities beyond what human biology ordinarily provides."

Standard tissue engineering involves seeding types of cells, such as those that form ear cartilage, onto a scaffold of a polymer material called a hydrogel. However, the researchers said that this technique has problems replicating complicated three dimensional biological structures. Ear reconstruction "remains one of the most difficult problems in the field of plastic and reconstructive surgery," they wrote.

To solve the problem, the team turned to a manufacturing approach called 3D printing. These printers use computer-assisted design to conceive of objects as arrays of thin slices. The printer then deposits layers of a variety of materials -- ranging from plastic to cells -- to build up a finished product. Proponents say additive manufacturing promises to revolutionize home industries by allowing small teams or individuals to create work that could previously only be done by factories.

Creating organs using 3D printers is a recent advance; several groups have reported using the technology for this purpose in the past few months. But this is the first time that researchers have demonstrated that 3D printing is a convenient strategy to interweave tissue with electronics.

The technique allowed the researchers to combine the antenna electronics with tissue within the highly complex topology of a human ear. The researchers used an ordinary 3D printer to combine a matrix of hydrogel and calf cells with silver nanoparticles that form an antenna. The calf cells later develop into cartilage.

Manu Mannoor, a graduate student in McAlpine's lab and the paper's lead author, said that additive manufacturing opens new ways to think about the integration of electronics with biological tissue and makes possible the creation of true bionic organs in form and function. He said that it may be possible to integrate sensors into a variety of biological tissues, for example, to monitor stress on a patient's knee meniscus.

David Gracias, an associate professor at Johns Hopkins and co-author on the publication, said that bridging the divide between biology and electronics represents a formidable challenge that needs to be overcome to enable the creation of smart prostheses and implants.

"Biological structures are soft and squishy, composed mostly of water and organic molecules, while conventional electronic devices are hard and dry, composed mainly of metals, semiconductors and inorganic dielectrics," he said. "The differences in physical and chemical properties between these two material classes could not be any more pronounced."

The finished ear consists of a coiled antenna inside a cartilage structure. Two wires lead from the base of the ear and wind around a helical "cochlea" -- the part of the ear that senses sound -- which can connect to electrodes. Although McAlpine cautions that further work and extensive testing would need to be done before the technology could be used on a patient, he said the ear in principle could be used to restore or enhance human hearing. He said electrical signals produced by the ear could be connected to a patient's nerve endings, similar to a hearing aid. The current system receives radio waves, but he said the research team plans to incorporate other materials, such as pressure-sensitive electronic sensors, to enable the ear to register acoustic sounds.

In addition to McAlpine, Verma, Mannoor and Gracias the research team includes: Winston Soboyejo, a professor of mechanical and aerospace engineering at Princeton; Karen Malatesta, a faculty fellow in molecular biology at Princeton; Yong Lin Kong, a graduate student in mechanical and aerospace engineering at Princeton; and Teena James, a graduate student in chemical and biomolecular engineering at Johns Hopkins.

The team also included Ziwen Jiang, a high school student at the Peddie School in Hightstown who participated as part of an outreach program for young researchers in McAlpine's lab.

"Ziwen Jiang is one of the most spectacular high school students I have ever seen," McAlpine said. "We would not have been able to complete this project without him, particularly in his skill at mastering CAD designs of the bionic ears."

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Princeton University, Engineering School, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Manu S Mannoor, Ziwen Jiang, Teena James, Yong Lin Kong, Karen A Malatesta, Winston Soboyejo, Naveen Verma, David H Gracias, Michael C. McAlpine. A 3D Printed Bionic Ear. Nano Letters, 2013; : 130501101451003 DOI: 10.1021/nl4007744

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/zUICGgK3jVo/130501193208.htm

new jersey atlantic city ocean city maryland Nexus 7 KDKA Pumpkin Carving Ideas Hurricane Sandy path